Special note: Half of her kittens will carry 1 copy of  Pyruvate Kinase (PK) Deficiency. Which one copy is not an issue at all. This disease is autosomal recessive meaning that two copies of the mutation are needed for disease signs to be shown. A carrier cat with one copy of the Pyruvate Kinase Deficiency mutation can be safely bred with a clear cat with no copies of the Pyruvate Kinase Deficiency mutation. About half of the kittens will have one copy (carriers) and half will have no copies of the Pyruvate Kinase Deficiency mutation. Kittens in a litter which is expected to contain carriers should be tested prior to breeding. Carrier to carrier matings are not advised as the resulting litter may contain affected kittens.

 

You can read more about PKDef here…